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Overview

Generalities
Agent Virus : Hepatitis A virus HAV.
Incubation 28-30 days (15-50 days).
Period of communicability During the second half of the incubation period, and up to one week after jaundice onset.
Reservoir Humans, rarely chimpanzees and other primates.
Modes of transmission -Person-to-person transmission: fecal oral route.
-Ingestion of contaminated food: by food handler or by harvested from contaminated water (shellfish or salad vegetables)
-Ingestion of contaminated water or drinks
-Recipients of factor VIII or factor IX concentrates.
Clinical -Febrile jaundice.
-Asymptomatic in childhood.
-Case fatality: 0.1-0.3 % (1.8% for >50 years) secondary to fulminant acute hepatitis.
Worldwide -Worldwide, related to hygienic and sanitary conditions.
-High endemicity: childhood infection, no outbreaks.
-Middle endemicity: outbreaks among adults.
-Low endemicity: cases among households, sexual contacts, day care centers…
Lebanon Endemic with middle endemicity profile.
Control objective Control.
National figures
Figure 1:
International figures (source: WHO. The Global prevalence of hepatitis A virus infection and susceptibility: a systematic review. WHO/IVB/10.01 2010)
Table 1:
 
 
 

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